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Figure 3 | Algorithms for Molecular Biology

Figure 3

From: Efficient unfolding pattern recognition in single molecule force spectroscopy data

Figure 3

The flow of the analysis procedure: First, F-D curves are denoised. Next, we transform the curves to derivatives that represent increasing, decreasing, or constant force. Next, we detect the unfolding events as peaks in the curves. An alignment procedure matches peaks between curves that correspond to the same unfolding event. The unfolding patterns are constructed this way, by matching corresponding unfolding events between curves.

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