Table 6 Comparison in terms of biological relevance between each pair of conserved protein complexes predicted by each method based one AlignNemo’s dataset
Methods | Yeast-fly | ||||
|---|---|---|---|---|---|
Conserved pairs | \(Avg\_mixed\) | \(Avg\_yeast\) | \(Avg\_fly\) | \(Avg\_intra\) | |
UEDAMAlignCFinder (k = 4) | 126 | 2.669 | 4.9984 | 1.8629 | 2.5173 |
UEDAMAlignCMC | 127 | 2.3109 | 4.669 | 1.661 | 2.223 |
UEDAMAlignCoach | 1,019 | 2.0566 | 3.784 | 1.5193 | 2.0422 |
UEDAMAlignKnownComplex | 160 | 2.7962 | 7.16 | 1.7741 | 2.4475 |
UEDAMAlignMCL | 697 | 1.9411 | 3.0208 | 1.3032 | 1.6191 |
AlignNemo | 248 | 1.7501 | 3.5919 | 0.916 | 1.3803 |
AlignMCL | 683 | 1.2522 | 2.283 | 1.019 | 1.4451 |
Methods | Human-fly | ||||
|---|---|---|---|---|---|
Conserved pairs | \(Avg\_mixed\) | \(Avg\_human\) | \(Avg\_fly\) | \(Avg\_intra\) | |
UEDAMAlignCFinder (k = 4) | 116 | 3.7834 | 4.0505 | 3.583 | 3.7361 |
UEDAMAlignCMC | 288 | 3.7938 | 4.2582 | 3.6216 | 3.6653 |
UEDAMAlignCoach | 2,978 | 3.6269 | 3.9705 | 3.4952 | 3.5129 |
UEDAMAlignKnownComplex | 333 | 4.8623 | 5.9331 | 4.5124 | 4.5783 |
UEDAMAlignMCL | 679 | 2.3677 | 2.3178 | 2.1294 | 2.3791 |
AlignNemo | 114 | 2.7493 | 2.9498 | 2.7695 | 2.5799 |
AlignMCL | 732 | 2.2485 | 2.2044 | 1.7298 | 2.2649 |