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Table 2 Prediction performance of ExAlt. Sensitivity (Sens) and Specificity (Spec) are shown for exons.

From: A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons

  Constitutive Cassete Multiple Splice Intron Retention All Exons
  Sens Spec Sens Spec Sens Spec Sens Spec Sens Spec
ExAlt-Exon 100 96 100 89 67 94 61 89 84 94
N-SCAN-Exon Union 100 86 100 89 65 79 55 78 82 84
Augustus-Exon Union 100 82 100 81 63 77 52 73 81 79
SNAP-Exon Union 100 77 100 79 64 74 51 76 81 77
SNAP+N-SCAN-Exon Union 100 73 100 74 69 68 57 70 83 72
Augustus+N-SCAN-Exon Union 100 79 100 77 68 73 57 68 83 76
Aug.+SNAP+N-SCAN-Exon Union 100 70 100 69 71 64 60 64 84 67
  1. Columns are organized by exon type: Constitutive, Cassette, Multiple Splice, Intron Retention, and all exons counted together (All Exons). Row 1 shows ExAlt performance using an input exon and default parameter settings (ExAlt-Exon). Rows 2–6 show the union of different combinations of three gene finders (N-SCAN, SNAP, and Augustus) plus the input exon. (Aug. = Augustus)