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Table 1 A Simple Motif

From: SMOTIF: efficient structured pattern and profile motif search

Symbols

Motif

A

0

0

0

4

1

1

7

0

5

1

0

2

0

2

0

0

0

C

10

0

1

2

3

5

0

7

0

4

2

5

5

1

9

10

0

G

0

10

9

4

5

3

2

3

0

3

1

1

4

1

1

0

10

T

0

0

0

0

1

1

1

0

5

2

7

2

1

6

0

0

0

IUPAC

C

G

S

V

N

N

D

S

W

N

B

N

B

N

S

C

G

  1. The binding sites for the transcription factor GAL4 in S. cerevisiae satisfy this motif [1]. Rows 2–5 show the profile (the frequency of observing a DNA base in a given position). The last row shows the corresponding pattern over the IUPAC alphabet.