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Table 2 Number of e-value smaller than a threshold are given for exact computations (exact) and asymptotic Karlin's approximations (Karlin). The last row gives the accuracy of asymptotic predictions (accuracy = Karlin/exact).

From: Effective p-value computations using Finite Markov Chain Imbedding (FMCI): application to local score and to pattern statistics

e-value 10-1 10-2 10-3 10-4 10-5 10-6
exact 9473 7772 6271 4563 3232 2348
Karlin 3417 2047 1056 439 195 96
accuracy 34% 26% 17% 10% 6% 4%