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Table 2 Number of e-value smaller than a threshold are given for exact computations (exact) and asymptotic Karlin's approximations (Karlin). The last row gives the accuracy of asymptotic predictions (accuracy = Karlin/exact).

From: Effective p-value computations using Finite Markov Chain Imbedding (FMCI): application to local score and to pattern statistics

e-value

10-1

10-2

10-3

10-4

10-5

10-6

exact

9473

7772

6271

4563

3232

2348

Karlin

3417

2047

1056

439

195

96

accuracy

34%

26%

17%

10%

6%

4%