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Figure 1 | Algorithms for Molecular Biology

Figure 1

From: Analysis of computational approaches for motif discovery

Figure 1

Objective function: p- Value of log likelihood ratio in negative logarithm scale. The figure exhibits the comparison of the p-value of the log likelihood ratio between the planted motifs ("TFBS" in the legend) and that of MEME's predictions for selected datasets from [1]: we use only "Generic" and "Markov" among the three types of datasets (see [1]), because in "Real" type datasets the predictions are possibly genuine binding sites of some unannotated transcription factor other than the ones planted. The datasets are sorted in ascending order of TFBS scores for clarity. For each dataset, there are two scores: the score of TFBS and the score of MEME's prediction. Points on the x-axis correspond to the datasets for which MEME didn't make any prediction.

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