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Table 2 Comparison of p-values calculated by the AHOPRO program, by Monte Carlo simulations and by compound Poisson distribution formula under the M0 model

From: Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules

MOTIF, CUTOFF OCC. AHOPRO MONTE CARLO POISSON AHOPRO/MC AHOPRO/POISSON
bcd, 5.3 3 0.012 0.012 0.010 1.00 1.10
kr, 5.0 4 0.0044 0.0044 0.0033 1.01 1.34
hb, 6.2 2 0.013 0.013 0.012 0.99 1.04
bcd & kr 3&4 0.00025 0.00026 3.6E-05 0.99 7.10
bcd & kr & hb 3&4&2 6.54E-06 5.8E-06 4.34E-07 1.13 7.13
  1. Comparison of p-values calculated for the Markov(0) model by the AHOPRO program with p-values calculated by Monte Carlo simulations and by Poisson formula for motifs of D. melanogaster developmental transcription factors bicoid, kruppel and hunchback.