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Table 2 Granularity required for accurate computation with From P-value to Score. This table indicates the granularity value that is required for FROM P-VALUE TO SCORE to compute the accurate score threshold without any error. Each row of the table corresponds to a P-value: 10-3, 10-4, 10-5, and 10-6. Each cell gives the percentage of matrices for which FROM P-VALUE TO SCORE ends at the granularity of the corresponding column. For example, 52.4% matrices need a granularity larger than or equal to 10-3 when computing threshold for P-value 10-5.

From: Efficient and accurate P-value computation for Position Weight Matrices

 

Granularity

P-value

1e-1

1e-2

1e-3

1e-4

1e-5

1e-6

1e-7

1e-8

1e-9

1e-3

9

22.9

39.3

63.1

77.8

88.5

91.8

95.1

100

1e-4

7.7

20.2

49

70.2

85.6

92.3

97.1

99

100

1e-5

1.2

25.6

52.4

76.8

88.4

94.2

96.5

96.5

100

1e-6

5.4

42.7

66.7

82.7

94.7

96

98.7

98.7

100