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Table 1 Fit parameters of the modified Gumbel distribution Eq. (18) using the BLOSUM62 scoring matrix and affine gap costs with α = 10, β = 1 . 104 λ 2 extra MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaiiGacqWF7oaBdaqhaaWcbaGaeGOmaidabaGaeeyzauMaeeiEaGNaeeiDaqNaeeOCaiNaeeyyaegaaaaa@3671@ describes the estimated value of λ2 using the scaling relation Eq. (19). Fit parameters for other scoring systems are provided as supplementary material to this artilce [see additional file 1].

From: Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail

L, M

λ

104 λ2

K

S0

χ ∗ 2 MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaiiGacqWFhpWydaqhaaWcbaGaey4fIOcabaGaeGOmaidaaaaa@3078@

104 λ 2 extra MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaiiGacqWF7oaBdaqhaaWcbaGaeGOmaidabaGaeeyzauMaeeiEaGNaeeiDaqNaeeOCaiNaeeyyaegaaaaa@3671@

40

0.3272 ± 0.108%

8.6347 ± 0.412%

0.1028 ± 0.65%

15.597 ± 0.0676%

79.05

8.1560 ± 12.485%

60

0.3034 ± 0.086%

6.2007 ± 0.285%

0.0751 ± 0.60%

18.455 ± 0.0645%

49.40

6.1711 ± 12.907%

80

0.2892 ± 0.070%

4.8781 ± 0.222%

0.0612 ± 0.53%

20.644 ± 0.0540%

21.67

5.0458 ± 13.280%

100

0.2747 ± 0.072%

4.3187 ± 0.330%

0.0472 ± 0.58%

22.413 ± 0.0611%

39.42

4.3056 ± 13.627%

150

0.2541 ± 0.083%

3.2974 ± 0.529%

0.0303 ± 0.61%

25.682 ± 0.0422%

39.46

3.2047 ± 14.437%

200

0.2432 ± 0.063%

2.6343 ± 0.344%

0.0241 ± 0.52%

28.257 ± 0.0412%

10.47

2.5806 ± 15.214%

250

0.2359 ± 0.071%

2.1999 ± 0.454%

0.0198 ± 0.60%

30.196 ± 0.0459%

9.40

2.1701 ± 15.984%

300

0.2303 ± 0.061%

1.9101 ± 0.348%

0.0174 ± 0.54%

31.934 ± 0.0408%

2.00

1.8758 ± 16.758%

350

0.2261 ± 0.046%

1.6404 ± 0.239%

0.0153 ± 0.41%

33.334 ± 0.0300%

1.27

1.6525 ± 17.544%

400

0.2224 ± 0.052%

1.4806 ± 0.266%

0.0136 ± 0.49%

34.556 ± 0.0369%

1.36

1.4762 ± 18.347%

600

0.2140 ± 0.062%

1.0206 ± 0.384%

0.0106 ± 0.64%

38.561 ± 0.0472%

2.15

1.0250 ± 21.787%

800

0.2090 ± 0.063%

0.7660 ± 0.419%

0.0088 ± 0.67%

41.320 ± 0.0457%

1.82

0.7691 ± 25.697%