Figure 1

Hook-analysis of hybridizations on the human genome HG-U95 (left panel) and Drosophila genome DG-1 (right panel) GeneChips taken from the Genelogic dilution [1] and the GoldenSpike [2] experimental series: The upper panel shows the raw and the sensitivity-corrected hook curves, the fitted theoretical curve and the distribution of the Σ-signal values (right axis, only left panel). Each hybridization is characterized by the parameters given in the figure (see also Table 2). These chip-characteristics are obtained from the fit. They are related to the geometrical dimensions of the corrected hook curve (see text). The lower part in each panel shows the four sensitivity profiles: PM-N and MM-N (left) and PM-S and MM-S (right).