Figure 12

Δ-vs-Σ trajectory (part a), the S/N ratios of the PM, MM and of their mean (Eqs. (46) and (18), part b) and the fraction of occupied PM and MM probes (occupancy, Eq. (42), part c). The total occupancy additively decomposes into the occupancy due to specific and non-specific hybridization (thin lines, see Eq. (43)). Note that the latter occupancy is not a constant but it depletes upon increasing total occupancy because specific binding progressively replaces non-specific one.