A scoring matrix approach to detecting miRNA target sites

Table 3 Leave one out analysis

Drosophila melanogaster, miR-7
Target	LOO score	⩾ LOO score
CG12487.3/223–241	0.946	94
CG5185.3/279–297	1.000	34
CG3096.3/152–170	1.000	34
CG12487.3/250–268	1.000	34
CG3166.3/1100–1118	0.951	76
CG6096.3/103–121	1.000	34
CG8346.3/78–96	0.966	58
CG5185.3/334–352	1.000	34
CG6494.3/447–465	0.919	155
CG6096.3/24–42	1.000	34
CG6096.3/68–86	0.961	65
CG8328.3/63–81	0.773	2015
CG3166.3/1586–1602	0.855	393
CG3166.3/29–46	0.845	513
CG3166.3/1294–1312	0.861	521
*Caenorhabditis elegans* , let-7
Target	LOO score	⩾ LOO score
ZK792.6/247–264	0.959	3561
F38A6.1a/271–288	1.000	1708
C18D1.1.1/526–542	0.906	10458
ZK792.6/666–683	0.959	3522
ZK792.6/458–475	0.929	7311
F38A6.1a/133–150	0.874	19177
C01G8.9a/21–38	0.850	23906
ZK792.6/132–148	0.859	20570
C01G8.9a/159–175	0.813	30895
ZK792.6/190–207	0.807	41812
C12C8.3a/693–709	0.791	39369
C12C8.3a/742–757	1.000	1499
ZK792.6/484–499	0.898	10232
F11A1.3a/1007–1021	0.948	4658
ZK792.6/343–361	0.955	4352
*Drosophila melanogaster* , miR-4
Target	LOO score	⩾ LOO score
CG6096.3/135–154	0.755	3118
CG8328.3/27–45	1.000	8
CG3096.3/33–52	0.929	161
CG3096.3/138–157	0.877	473
CG5185.3/46–65	0.960	64
CG12487.3/188–208	0.820	1298
CG12487.3/62–82	0.871	627
CG6096.3/210–230	0.908	207
*Caenorhabditis elegans* , miR-84
Target	LOO score	⩾ LOO score
ZK792.6/126–148	0.804	4970
ZK792.6/187–207	0.552	132626
ZK792.6/249–264	0.947	355
ZK792.6/342–361	0.761	12552
ZK792.6/460–475	0.858	2012
ZK792.6/479–499	0.739	18375
ZK792.6/665–683	0.726	15846

"target" gives validated target sequence accession/start-end; "miRNA" gives miRNA targeting that region; "⩾ LOO score" gives mean number of regions scoring equal to or greater than the left out sequence.

ISSN: 1748-7188