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Table 1 Sex-specific differences observed in haplotype frequencies and higher-order linkage disequilibria estimates

From: Modeling genetic imprinting effects of DNA sequences with multilocus polymorphism data

  Male Female Sex-specific Sex-specific
Genetic Parameter MLE p-value MLE p-value LR p-value
Haplotype Frequency
GAC 0.780   0.764    
GAT 0.000   0.000    
GGC 0.124   0.081    
GGT 0.011   0.023    
TAC 0.049   0.104    
TAT 0.000   0.000    
TGC 0.008   0.000    
TGT 0.030   0.029    
Allele Frequency and Linkage Disequilibrium
G (OPRKG36T) 0.914   0.868   6.166 0.0130
A (OPRKA843G) 0.828   0.868   3.501 0.0613
A (OPRKC846T) 0.960   0.949   2.943 0.0862
12 0.034 0.0459 0.045 0.1812 5.771 0.0163
23 0.026 4.98e-6 0.022 3.61e-6 42.281 7.91e-11
13 0.023 8.87e-5 0.011 0.0089 22.216 2.44e-6
123 -0.021 2.53e-4 -0.018 0.0055 21.088 4.39e-6
  1. Estimates and tests of population genetic structure for three SNPs, OPRKG36T (with two alleles G and T), OPRKA843G (with alleles A and G), and OPRKC846T (with alleles C and T), at the kappa-opioid receptor in males and females.