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Table 3 Additive, dominant, imprinting, and overall effects at three SNPs

From: Modeling genetic imprinting effects of DNA sequences with multilocus polymorphism data

Trait

 

Risk Haplotype

a

d

i

Overall

PreInt49tot

Effect

GAC

-13.47

-6.22

19.02

 
 

p-value

 

0.005

0.237

0.008

0.004

Hpthpent

Effect

TAC

3.06

3.08

-0.26

 
 

p-value

 

0.002

0.003

0.089

0.023

Hptopent

Effect

TAC

2.15

2.33

-0.28

 
 

p-value

 

0.003

0.003

0.621

0.025

  1. Estimates of additive (a), dominant (d), and imprinting effects (i) of haplotypes at SNPs, OPRKG36T (with two alleles G and T), OPRKA843G (with alleles A and G), and OPRKC846T (with alleles C and T), at the kappa-opioid receptor, on pain sensitivity traits.
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Algorithms for Molecular Biology

ISSN: 1748-7188