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Figure 2 | Algorithms for Molecular Biology

Figure 2

From: Linear model for fast background subtraction in oligonucleotide microarrays

Figure 2

Fitted vs. solution hybridization free energies. Pair Parameters α (19 ≤ α ≤ 34), as obtained from the minimization of Eq. (4) as function of ΔG α , the nearest-neighbor stacking free energy obtained from DNA/RNA hybridization in solution [20]. Plots refer to two GSE training data sets of a) C. Elegans and b) Drosophila Melanogaster. Each point on the y-axis is the averaged value over all CEL-files representing its GSE-set. The error bars are the standard deviation. Notation of DNA pairs are from 5' to 3' end. The straight lines are linear fits; correlation coefficients of each GSE set in legend.

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