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Figure 7 | Algorithms for Molecular Biology

Figure 7

From: An image processing approach to computing distances between RNA secondary structures dot plots

Figure 7

P5abc subdomain. The predicted most significant mutation for the P5abc subdomain in the group I intron ribozyme of the T. thermophila. (A) Wild-type folded structure along with its representing dot plot matrix. The computed RNAfold global minimum energy is dG = -26.6. (B) The mutated folded structure with the largest distance grade from DoPloCompare (DP) = 0.102. The RNAdistance grade for this structure (Rdist) = 28. The computed RNAfold global minimum energy is dG = -18.8. (C) The mutated folded structure with the largest RNAdistance grade (Rdist) = 32. The DoPloCompare grade (DP) = 0.070. The computed RNAfold global minimum energy is dG = -22.2 kcals/mole.

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