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Figure 8 | Algorithms for Molecular Biology

Figure 8

From: An image processing approach to computing distances between RNA secondary structures dot plots

Figure 8

Delta virusoid. The predicted most significant mutation for the virusoid sequence from Hepatitis delta virus. (A) Wild-type folded structure along with its representing dot plot matrix. The computed RNAfold global minimum energy is dG = -68.6. (B) The mutated folded structure with the largest distance grade from DoPloCompare (DP) = 0.023. The RNAdistance grade for this structure (Rdist) = 60. The computed RNAfold global minimum energy is dG = -67.5. (C) The mutated folded structure with the largest RNAdistance grade (Rdist) = 62. The DoPloCompare grade (DP) = 0.022. The computed RNAfold global minimum energy is dG = -63.7 kcals/mole.

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