Association of repeatedly measured intermediate risk factors for complex diseases with high dimensional SNP data

Waaijenborg, Sandra; Zwinderman, Aeilko H

doi:10.1186/1748-7188-5-17

Algorithms for Molecular Biology

Table 2 Selected SNPs in the Framingham heart study.

From: Association of repeatedly measured intermediate risk factors for complex diseases with high dimensional SNP data

Chrom	Position	ID	Gene symbol	Loadings	Cross-loadings
First canonical variate
6	36068368	rs17707331	SLC26A8	0.03	0.10
6	36088099	rs743923	SLC26A8	0.02	0.10
8	62213297	rs17763714		0.02	0.10
16	55550825	rs3764261	near CETP	1.00	0.23
17	39634367	rs9303601		-0.00	0.10
Second canonical variate
1	54388154	rs11576359	CDCP2	0.07	0.09
1	70656428	rs1145920	CTH	0.17	0.10
1	82015671	rs12072054		0.09	0.09
2	28371365	rs4666051	BRE	0.15	0.10
2	33358643	rs2290427	LTBP1	0.11	0.09
2	49052952	rs12713027	FSHR	0.41	0.10
2	49074650	rs4494802	FSHR	0.67	0.14
2	177267412	rs16864244	LOC375295	0.08	0.09
3	122662360	rs669277	POLQ	0.15	0.09
3	122669112	rs532411	POLQ	0.14	0.09
4	178830262	rs13149928		0.19	0.10
5	79069147	rs2278240	CMYA5	0.19	0.10
6	33380833	rs2071888	TAPBP	0.13	0.10
6	42374980	rs4714595	TRERF1	0.06	0.08
6	102197213	rs6925691	GRIK2	0.25	0.11
6	116504475	rs12527159		0.23	0.10
7	116990653	rs213952	CFTR	0.11	0.10
7	129737976	rs2171492	CPA4	0.22	0.10
7	129771213	rs7786598	CPA5	0.27	0.09
7	129772024	rs1532047	CPA5	0.29	0.10
7	137639294	rs410156		0.08	0.09
8	23574003	rs7006278		0.07	0.09
10	71959784	rs2275060	KIAA1274	0.15	0.09
10	81916682	rs1049550	ANXA11	0.18	0.10
11	12036827	rs2403569		0.07	0.08
11	24693192	rs2631439	LUZP2	0.14	0.09
11	33438534	rs2615913		0.20	0.10
11	92329680	rs7936247		0.11	0.09
11	101990763	rs7126560	MMP20	0.23	0.10
11	133808516	rs7949167		0.07	0.08
12	7040597	rs12146727	C1S	0.23	0.10
12	14873619	rs3088190	ART4	0.11	0.09
13	95455188	rs16951415	UGCGL2	0.13	0.09
14	59141031	rs10483717	RTN1	0.29	0.11
15	64238853	rs4776752	MEGF11	0.15	0.09
16	15548316	rs9930648	C16orf45	0.05	0.08
16	77671528	rs12935535	WWOX	0.11	0.09
17	53939507	rs2302190	MTMR4	0.14	0.10
19	38606005	rs11084731	PEPD	0.29	0.11
22	37171988	rs196084	KCNJ4	0.09	0.09

Selected SNPs within the first and second canonical variate pair, together with their loadings and cross-loadings.

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ISSN: 1748-7188

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