Table 1 Filter impact
From: Optimal selection of epitopes for TXP-immunoaffinity mass spectrometry
Filter | # epitopes | # proteins | # combinations |
|---|---|---|---|
Unfiltered | 671,427 | 20,333 | 4,196,636 |
unknown positions filter | 671,253 | 20,333 | 4,195,788 |
methionine filter | 569,365 | 20,332 | 3,839,772 |
high abundant epitope filter | 569,354 | 20,332 | 3,312,617 |
weight filter | 559,323 | 20,178 | 1,962,034 |
length filter | 530,863 | 20,020 | 1,662,437 |
high abundant protein filter | 527,164 | 20,010 | 1,598,289 |
- Impact of the different filters applied on the in-silico tryptic digest of the human proteome (Uniprot taxon id 9606), N-C-terminal epitopes of length 4 and 5, Δ
min
= 4,
