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Table 1 Benchmark results for the artificially generated data and the LacI family.

From: An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies

 

Sensitivity

False positive rate

Distance

Generated family 1

1.00

0.00

0.00

Generated family 2

1.00

0.00

0.00

LacI family

0.15

0.03

0.08

  1. For the generated data, SDPs were introduced after the mutation process, for the LacI family, all positions that alter protein function according to [21] were considered SDPs.