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Table 4 Sensitivity, false positive rate, average and median distances to the ligand for predictions obtained with different methods for the enzyme dataset.

From: An automated stochastic approach to the identification of the protein specificity determinants and functional subfamilies

  Sensitivity False positive rate Average distance to the ligand Median distance to the ligand
dataset1     
Trace Suite II 0.78 0.55 12.27 11.77
FASS 0.04 0.01 9.82 11.42
MB-method 0.13 0.05 9.67 8.67
S-method 0.04 0.01 9.66 12.92
rate4site 0.26 0.16 11.91 11.74
SDPclust 0.10 0.04 10.96 10.96
SDPsite 0.14 0.13 12.71 12.62
dataset2     
Trace Suite II 0.69 0.51 12.26 11.88
FASS 0.07 0.01 8.80 9.62
MB-method 0.15 0.06 9.89 9.86
S-method 0.07 0.01 6.84 6.90
rate4site 0.21 0.15 12.59 12.40
SDPclust 0.12 0.06 10.81 11.08
SDPsite 0.16 0.11 11.46 11.17
  1. All positions that lie closer than 10 Å to the co-crystallized ligand in the corresponding structure are considered SDPs.