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Table 5 Accuracy and MCC values for k-fold CV using LP, SVM, and Lasso models, when the folds are created using sequence similarity scores.

From: Scoring function to predict solubility mutagenesis

  LP SVM Lasso
k -fold ACC MCC ACC MCC ACC MCC
19 0.504 0.289 0.569 -0.056 0.569 -*
30 0.642 0.279 0.511 -0.075 0.584 0.140
50 0.650 0.289 0.409 -0.185 0.708 0.448
70 0.686 0.364 0.650 0.269 0.708 0.448
  1. Key: k = 19 represents leave one protein out CV. There was no MCC value (denoted by -*) for predictions by the Lasso model in this case, as all mutants were predicted to see a decrease in solubility.