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Table 5 Accuracy and MCC values for k-fold CV using LP, SVM, and Lasso models, when the folds are created using sequence similarity scores.

From: Scoring function to predict solubility mutagenesis

 

LP

SVM

Lasso

k -fold

ACC

MCC

ACC

MCC

ACC

MCC

19

0.504

0.289

0.569

-0.056

0.569

-*

30

0.642

0.279

0.511

-0.075

0.584

0.140

50

0.650

0.289

0.409

-0.185

0.708

0.448

70

0.686

0.364

0.650

0.269

0.708

0.448

  1. Key: k = 19 represents leave one protein out CV. There was no MCC value (denoted by -*) for predictions by the Lasso model in this case, as all mutants were predicted to see a decrease in solubility.