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Table 3 Performance of genetic algorithm and overall algorithm

From: Predicting direct protein interactions from affinity purification mass spectrometry data

Network (i) reduced network (ii) overall network
  real pred. FDR(%) FNR(%) real pred. FDR(%) FNR(%)
Yu 563 552 43.65 44.76 1318 1390 14.96 10.31
DIP 931 890 35.50 38.34 1967 2041 17.34 14.23
PAM 473 421 49.88 55.39 1538 1462 16.14 20.28
DM 1138 1295 43.39 35.58 1869 1804 32.81 35.15
  1. (i) Performance of the genetic algorithm on the reduced network obtained from removing 1-cut vertices and degree-2 vertices. (ii) Overall performance of the combined prediction pipeline on the complete connectivity matrix. Real and predicted describe the number of edges in the real and predicted networks, respectively.