Table 2 GO molecular functions enriched in the putative modifiers detected for the TF-Gene pairs in S. cerevisiae based on ChIP-chip data and 314 expression samples.
From: Mimosa: Mixture model of co-expression to detect modulators of regulatory interaction
Molecular function term | % Coverage | p-value | FDR (%) |
|---|---|---|---|
catalytic activity | 43 | 1.32E-04 | 0.22 |
nucleotide binding | 14 | 1.27E-05 | 0.02 |
purine nucleotide binding | 13 | 4.74E-05 | 0.08 |
purine ribonucleotide binding | 12 | 1.49E-05 | 0.02 |
ribonucleotide binding | 12 | 1.49E-05 | 0.02 |
RNA binding | 11 | 1.60E-09 | 2.71E-06 |
structural molecule activity | 10 | 4.34E-12 | 7.36E-09 |
structural constituentof ribosome | 9 | 4.38E-22 | 7.43E-19 |
GTP binding | 3 | 7.43E-06 | 0.01 |
guanyl nucleotide binding | 3 | 7.43E-06 | 0.01 |
guanyl ribonucleotide binding | 3 | 7.43E-06 | 0.01 |
oxidoreductase activity, acting on CH-OH group of donors | 3 | 4.66E-05 | 0.08 |
translation regulator activity | 3 | 8.71E-07 | 1.48E-03 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 3 | 1.10E-04 | 0.19 |
translation factor activity, nucleic acid | 3 | 2.14E-07 | 3.62E-04 |
GTPase activity | 2 | 2.39E-03 | 3.98 |
rRNA binding | 2 | 8.85E-11 | 1.50E-07 |
snoRNA binding | 2 | 8.58E-09 | 1.45E-05 |
ligase activity, forming aminoacyl-tRNA and related compounds | 2 | 1.33E-06 | 2.25E-03 |
ligase activity, forming carbon- oxygen bonds | 2 | 1.33E-06 | 2.25E-03 |
aminoacyl-tRNA ligase activity | 2 | 1.33E-06 | 2.25E-03 |
RNA helicase activity | 2 | 4.29E-05 | 0.07 |
ATP-dependent RNA Helicase activity | 2 | 9.12E-07 | 1.54E-03 |
RNA-dependent ATPase activity | 2 | 9.12E-07 | 1.54E-03 |
translation initiation factor activity | 1 | 4.61E-04 | 0.78 |