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Table 2 GO molecular functions enriched in the putative modifiers detected for the TF-Gene pairs in S. cerevisiae based on ChIP-chip data and 314 expression samples.

From: Mimosa: Mixture model of co-expression to detect modulators of regulatory interaction

Molecular function term % Coverage p-value FDR (%)
catalytic activity 43 1.32E-04 0.22
nucleotide binding 14 1.27E-05 0.02
purine nucleotide binding 13 4.74E-05 0.08
purine ribonucleotide binding 12 1.49E-05 0.02
ribonucleotide binding 12 1.49E-05 0.02
RNA binding 11 1.60E-09 2.71E-06
structural molecule activity 10 4.34E-12 7.36E-09
structural constituentof ribosome 9 4.38E-22 7.43E-19
GTP binding 3 7.43E-06 0.01
guanyl nucleotide binding 3 7.43E-06 0.01
guanyl ribonucleotide binding 3 7.43E-06 0.01
oxidoreductase activity, acting on CH-OH group of donors 3 4.66E-05 0.08
translation regulator activity 3 8.71E-07 1.48E-03
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3 1.10E-04 0.19
translation factor activity, nucleic acid 3 2.14E-07 3.62E-04
GTPase activity 2 2.39E-03 3.98
rRNA binding 2 8.85E-11 1.50E-07
snoRNA binding 2 8.58E-09 1.45E-05
ligase activity, forming aminoacyl-tRNA and related compounds 2 1.33E-06 2.25E-03
ligase activity, forming carbon- oxygen bonds 2 1.33E-06 2.25E-03
aminoacyl-tRNA ligase activity 2 1.33E-06 2.25E-03
RNA helicase activity 2 4.29E-05 0.07
ATP-dependent RNA Helicase activity 2 9.12E-07 1.54E-03
RNA-dependent ATPase activity 2 9.12E-07 1.54E-03
translation initiation factor activity 1 4.61E-04 0.78