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Figure 10 | Algorithms for Molecular Biology

Figure 10

From: Back-translation for discovering distant protein homologies in the presence of frameshift mutations

Figure 10

Elapidae: neurotoxins (2). Two Bungarus candidus proteins, very similar at the DNA level ([Swiss-Prot:Q8AY47.1] and [Swiss-Prot:Q8AY48.1]). From the first 94 amino acid pairs, only 4 present mismatches (which are transitions at the coding DNA level). A frameshift mutation is visible at position 284 of the back-translated sequences. The fragments following it are almost perfectly aligned with a frameshift, with an E-value of 10-9.

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