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Figure 12 | Algorithms for Molecular Biology

Figure 12

From: Back-translation for discovering distant protein homologies in the presence of frameshift mutations

Figure 12

Platelet-derived growth factor proteins. The alignment of the back-translated platelet-derived growth factor proteins from Homo sapiens and Ratus sp ([Swiss-Prot:P04085.1] and [DDBJ:BAA00987.1]). The two proteins share high similarity at the amino acid level on the subsequences 1-84 and 113-195. The amino acids 85-112 can be easily aligned with a frameshift, with an E-value of 10-6. Both the "inducing" and "correcting" frameshifts are located on two different exons.

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