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Table 2 The HDL cholesterol-related pathways detected

From: QTL/microarray approach using pathway information

  Map category Directionof change in gene expression* No. of genes No. of genes within QTL regions
Drug metabolism - cytochrome P450 Metabolism B 61 45
Glutathione metabolism Metabolism B 48 21
ABC transporters Environmental Information Processing D 37 16
Arachidonic acid metabolism Metabolism B 63 30
Linoleic acid metabolism Metabolism D 33 20
Histidine metabolism Metabolism D 22 10
Ascorbate and aldarate metabolism Metabolism D 12 11
Pentose phosphate pathway Metabolism B 24 10
Propanoate metabolism Metabolism D 26 14
Starch and sucrose metabolism Metabolism D 26 14
  1. *B and D represent bi-directional and down-regulation, respectively.