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Table 3 The IGF-1-related pathways detected

From: QTL/microarray approach using pathway information

  Map category Directionof change in gene expression* No. of genes No. of genes within QTL regions
All four comparisons     
PPAR signaling pathway Organismal Systems U 65 11
Drug metabolism - other enzymes Metabolism D 36 17
Three comparisons without B6 vs NZB     
ErbB signaling pathway Environmental Information Processing B 71 18
GnRH signaling pathway Organismal Systems B 88 27
MAPK signaling pathway Environmental Information Processing B 234 58
Steroid hormone biosynthesis Metabolism D 36 12
Gastric acid secretion Organismal Systems D 63 16
  1. *B, U and D represent bi-directional, up and down-regulation, respectively.