Table 3 The IGF-1-related pathways detected
| Â | Map category | Directionof change in gene expression* | No. of genes | No. of genes within QTL regions |
|---|---|---|---|---|
All four comparisons | Â | Â | Â | Â |
PPAR signaling pathway | Organismal Systems | U | 65 | 11 |
Drug metabolism - other enzymes | Metabolism | D | 36 | 17 |
Three comparisons without B6 vs NZB | Â | Â | Â | Â |
ErbB signaling pathway | Environmental Information Processing | B | 71 | 18 |
GnRH signaling pathway | Organismal Systems | B | 88 | 27 |
MAPK signaling pathway | Environmental Information Processing | B | 234 | 58 |
Steroid hormone biosynthesis | Metabolism | D | 36 | 12 |
Gastric acid secretion | Organismal Systems | D | 63 | 16 |