Properties of chromosome 1. (A) The aligned fragments for IgG, MAX and MAX normalized with IgG (left to right) are shown for the whole of chromosome 1. The intensities have been normalized to 0.1 within each signal with a darker colour representing more fragments. The large blank part of the figures is the centromeric region of chromosome 1. (B) Estimated distributions of fragment sizes for IgG, MAX and MAX normalized with IgG (left to right), based on distances between sense/anti-sense fragments using the approach taken in Johti et al . The plots are produced using the average over 10 bp distance-bins. The grey vertical line indicates the average distance and thus the estimate of the underlying fragment size.