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Figure 2 | Algorithms for Molecular Biology

Figure 2

From: Distributional fold change test – a statistical approach for detecting differential expression in microarray experiments

Figure 2

Application of an expression dependent threshold ( 14 ). Scatterplot of features in the two-dimensional space of log2(variance), average expression for two different pre-processing methods: MAS5 – left panel and RMA – right panel. Data from data set GSE6011 (see Table1) consisting of 37 samples. Blue dot represent features satisfying condition (11) and therefore considered as coming from null distribution. Green points represent features having total variance above expression dependent threshold and considered as non-nulls. On each panel, marginalized distributions of all and non-null features over variance is shown on the left side and marginalized distribution of all and non-null features over average expression is shown at the bottom of the panel.

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