Skip to main content

Table 1 Data sets from GEO database

From: Distributional fold change test – a statistical approach for detecting differential expression in microarray experiments

N

GEO data set

Experiment summary/Title

N A

N B

N PC

N Ka

1

GSE8441

Study of whether inadequate protein intake differentially affects skeletal muscle transcript levels and expression profiles in older adults[24]

11

11

9

5

2

GSE9499

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome[25]

15

7

77

6

3

GSE2638 and 2639

GSE2639: HUVEC were left untreated or stimulated for 5h with 2 ng/ml TNF. Comparsion of the gene profiles revealed TNF-mediated gene expression changes in HUVEC[26]. Study TNF stimulated vs controls.

7

7

13

8

4

GSE2638 and 2639

GSE2638: HMEC cultures were left untreated or stimulated for 5h with 2 ng/ml TNF. Comparison of the gene expression profiles revealed the TNF-mediated gene expression changes[26]. Study HMEC vs HUVEC

3

4

16

9

5

GSE3860

Comparison of Hutchinson–Gilford Progeria Syndrome fibroblast cell lines to control fibroblast cell lines[27].

9

9

8

11

6

GSE6344

Gene expression in Stage 1,2 Normal and Tumor kidney cancer[28]

10

10

19

15

7

GSE7765

Dioxin-induced gene expression changes in MCF-7 human breast cancer cells[29]

3

3

13

18

8

GSE6740_1

Comparison of transcriptional profiles of CD4+ and CD8+ T cells from HIV-infected patients and uninfected control group[30]. Study of CD4+ T cells

10

10

40

24

9

GSE6740_2

Comparison of transcriptional profiles of CD4+ and CD8+ T cells from HIV-infected patients and uninfected control group[30]. Study of CD8+ T cells

10

10

62

25

10

GSE6011

Expression data from quadriceps muscle of young DMD patients and age matched controls[31]

14

23

10

30

11

GSE2531

Total RNA from two commonly used choriocarcinoma cell lines, JEG3 and BeWo, are compared in this experiment to identify differentially expressed transcripts[32].

3

4

17

36

 

Total N P

   

284

 
  1. Data sets from GEO database[33], used for testing efficiency of DFC test. Samples in all data sets were profiled on Affymetrix GeneChip HG-U133A microarrays with 22283 probesets. Shortcuts: N A – number of samples in condition A, N B – number of samples in condition B, N PC – number of probesets checked by RT PCR. Total number of probesets, checked by RT PCR is 284. For easy access for data set’s detailed information we provide in the last column N Ka – data set’s number in the description file of ref[9].