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Table 3 Average AUC values for other six combinations.

From: A normalization strategy for comparing tag count data

 

PA = 50%

60%

70%

80%

90%

100%

 

(a) DESeq/TbT

     

PDEG = 5%

85.03

83.94

85.20

85.31

85.12*

84.60*

10%

86.94

86.90

87.42*

86.80*

87.61*

86.95*

20%

89.05

89.23

89.18*

89.33*

88.97*

88.95*

30%

90.30

90.20*

89.79*

90.11*

89.44*

88.80*

 

(b) DESeq/default

     

5%

85.03

83.92

85.13

85.19

84.84

84.18

10%

86.93

86.85

87.27

86.46

87.07

86.15

20%

89.06

89.19

88.93

88.62

87.76

86.84

30%

90.30

90.00

88.94

87.95

85.36

81.98

 

(c) baySeq/TbT

     

5%

89.91

89.45

89.91*

90.17*

89.93*

89.36*

10%

89.89

89.90*

90.46*

89.79*

90.28*

90.02*

20%

90.39*

90.46*

90.40*

90.49*

90.21*

90.47*

30%

90.80

90.55*

90.44*

90.69*

89.26*

88.33*

 

(d) baySeq/default

     

5%

89.67

89.27

88.62

88.69

86.37

86.18

10%

89.80

89.55

89.52

87.71

84.14

83.86

20%

90.22

88.78

88.92

87.85

79.09

69.65

30%

90.76

90.05

87.21

79.69

65.45

53.37

 

(e) NBPSeq/TbT

     

5%

90.75*

90.18

90.80*

90.90*

90.78*

90.33*

10%

90.59*

90.47*

91.00*

90.34*

91.14*

90.49*

20%

90.67*

90.72*

90.70*

90.68*

90.42*

90.37*

30%

90.92

90.83*

90.32*

90.74*

89.89*

89.23*

 

(f) NBPSeq/default

     

5%

90.48

90.00

89.71

89.58

87.85

87.60

10%

90.34

90.15

90.11

88.46

86.19

85.38

20%

90.39

89.12

89.22

88.29

81.59

73.93

30%

90.84

90.26

87.45

81.96

70.97

60.73

  1. Results for (a) DESeq/TbT, (b) DESeq/default, (c) baySeq/TbT, (d) baySeq/default, (e) NBPSeq/TbT, and (f) NBPSeq/default. Higher AUC values between different normalization methods in each package are in bold. AUC values with asterisks indicate significant improvements (p-value < 0.01, Wilcoxon rank sum test).