Algorithms for Molecular Biology

Table 7 E. coli data: classification-based results

From: MCOIN: a novel heuristic for determining transcription factor binding site motif width

Conservation	Known width (w^∗)			MCOIN (w^∗ ± 4)			E-values (w^∗x ± 4)
(mean bits/col)	sSn	sPPV	AUC	sSn	sPPV	AUC	sSn	sPPV	AUC
‘high’ (1.36)	0.81	0.22	0.96	0.72	0.29	0.96	0.70	0.17	0.95
‘low’ (0.78)	0.63	0.41	0.96	0.69	0.51	0.98	0.66	0.32	0.97
overall (1.13)	0.74	0.30	0.96	0.71	0.38	0.96	0.68	0.23	0.96

Mean site-level sensitivity (sSn), positive predictive value (sPPV) and area under the ROC curve (AUC) for 20 datasets created using realE. coli data.

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ISSN: 1748-7188

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