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Table 5 Validation results with GO hierarchy level limitations

From: Configurable pattern-based evolutionary biclustering of gene expression data

 

All levels

Levels 3 to 6

Levels 4 to 7

 

p-value

# Bics

#Terms ¯

# Bics

#Terms ¯

# Bics

#Terms ¯

Yeast

0.01

32

5.969

32

5.125

31

4.387

 

0.05

41

6.878

40

5.625

40

5.225

ET

0.01

3

3.000

3

3.000

3

2.666

 

0.05

9

3.778

9

3.444

9

3.333

Leukemia

0.01

4

1.000

3

1.000

3

1.000

 

0.05

12

2.333

11

1.454

11

1.818

Steminal

0.01

18

4.056

16

2.750

13

2.231

 

0.05

27

7.111

26

5.269

25

4.200

  1. Validation with Gene Ontology has been carried out for Evo-Bexpa biclusters of the four datasets in Table 3 using the default configuration. This table shows the number of significant biclusters and significant terms in three different validations: taking the whole hierarchical graph into account, and limiting the validation with the levels 3 to 6 and 4 to 7, both inclusive.
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Algorithms for Molecular Biology

ISSN: 1748-7188