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Table 2 CpG hypo-methylation in tissue-specific lncRNA promoters

From: Mutual enrichment in ranked lists and the statistical assessment of position weight matrix motifs

Tissue Mutual enrichment between GC content and tissue-specificity Mutual enrichment between hypo-methylation and tissue-specificity
Normal/subnormal cells Cancer cells
Thyroid 3.89e-31 No methylation data No methylation data
Prostate 5.76e-22 4.16e-11 (PrEC) 0.002 (LNCaP)
Adrenal 5.46e-20 No methylation data No methylation data
Brain 1.57e-14 1.21e-8 (NH-A) 5.55e-5 (U87)
Ovary 8.80e-12 No methylation data 0.0085 (ovcar-3)
Lymph node 3.64e-6 No methylation data No methylation data
Adipose 9.25e-6 No methylation data No methylation data
Foreskin 2.25e-5 0.72 (BJ) No methylation data
Breast 4.40e-5 5.08e-5 (HMEC) 8.45e-5 (MCF7)
2.0e-10 (MCF10A) 0.0065 (T-47D)
Kidney 6.34e-5 1.56e-5 (HEK293) No methylation data
White blood cell 3.78e-4 0.6 (GM12878) 0.21 (Jurkat)
Placenta 0.011 No methylation data No methylation data
Colon 0.012 No methylation data 1.0 (Caco-2)
Skeletal muscle 0.04 0.34 (SKMC) No methylation data
Lung 0.33 No methylation data No methylation data
Heart 1.0 1.0 (HCM) No methylation data
1.0 (HCF)
Liver 1.0 1.0 (Hepatocytes) 1.0 (HepG2)
Testes 1.0 No methylation data 1.0 (NT2-D1)
Lung fibroblasts 1.0 1.0 (IMR90) No methylation data
   1.0 (AGO4450)  
  1. We calculated the mutual enrichment between DNA hypo-methylation and tissue specificity for the lncRNA promoters. CpG methylation data was taken from UCSC Table Browser [39] (ENCODE/HAIB).