TY - JOUR AU - Goldstein, Yaron AB AU - Bockmayr, Alexander PY - 2015 DA - 2015/01/09 TI - Double and multiple knockout simulations for genome-scale metabolic network reconstructions JO - Algorithms for Molecular Biology SP - 1 VL - 10 IS - 1 AB - Constraint-based modeling of genome-scale metabolic network reconstructions has become a widely used approach in computational biology. Flux coupling analysis is a constraint-based method that analyses the impact of single reaction knockouts on other reactions in the network. SN - 1748-7188 UR - https://doi.org/10.1186/s13015-014-0028-y DO - 10.1186/s13015-014-0028-y ID - Goldstein2015 ER -