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Table 2 Average number of knockout options

From: Double and multiple knockout simulations for genome-scale metabolic network reconstructions

Model Single KOs Double KOs
  Options Options
E. coli iJO1366 35.1 143
E. coli iAF1260 26.4 78.0
S. cerevisiae iND750 25.6 106
M. tuberculosis iNJ661 82.7 120
S. aureus iSB619 65.9 245
H. pylori iIT341 143 126
E. coli textbook 6.92 132
  1. Single KOs options: Average number of reactions r that lead as single knockouts to inactivity of a target reaction t: $\boldsymbol {\frac {1}{|1_{L}|} \sum _{t\in 1_{L}}\sum _{r\stackrel {=0}{\rightarrow } t\,\text {in}\, L}}$ 1.
  2. Double KOs options: Average number of uncoupled reaction pairs {r, s} that lead as double knockouts to inactivity of a target reaction t: $\boldsymbol {\frac {1}{|1_{L}|} \sum _{t\in 1_{L}}\sum _{\{r, s\} \stackrel {=0}{\rightarrow }t\, \text {in}\,L}}$ 1.