Algorithms for Molecular Biology

Table 1 Docking accuracy comparison of MoDock with 6 commonly used docking programs

From: MoDock: A multi-objective strategy improves the accuracy for molecular docking

RMSD	Ratio
RMSD	MoDock	Glide ^a	GOLD ^b	Surflex ^c	FlexX ^d	DOCK6 ^e	Dock6-F ^f
≤0.5	0.40	0.29	0.08	0.16	0.03	0.15	0.09
≥0.5, ≤1.0	0.30	0.19	0.27	0.32	0.18	0.15	0.32
≥1.0, ≤1.5	0.07	0.12	0.20	0.14	0.14	0.19	0.28
≥1.5, ≤2.0	0.01	0.11	0.11	0.15	0.14	0.13	0.11
≥2.0, ≤2.5	0.03	0.06	0.02	0.04	0.06	0.04	0.07
≥2.5, ≤3.0	0.04	0.03	0.03	0.02	0.04	0.08	0.03
≥3.0	0.16	0.20	0.28	0.17	0.40	0.27	0.09
Avg. RMSD	1.53	1.98	3.19	2.15	3.69	2.13	1.46

^athe date are from reference [30].
^bthe date are from reference [29].
^cthe date are from reference [31].
^dthe date are from reference [32].
^ethe date are from reference [28].
^fthe date are derived from running Dock6 with default parameters.

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