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Table 1 Docking accuracy comparison of MoDock with 6 commonly used docking programs

From: MoDock: A multi-objective strategy improves the accuracy for molecular docking

RMSD Ratio  
MoDock Glide a GOLD b Surflex c FlexX d DOCK6 e Dock6-F f
≤0.5 0.40 0.29 0.08 0.16 0.03 0.15 0.09
≥0.5, ≤1.0 0.30 0.19 0.27 0.32 0.18 0.15 0.32
≥1.0, ≤1.5 0.07 0.12 0.20 0.14 0.14 0.19 0.28
≥1.5, ≤2.0 0.01 0.11 0.11 0.15 0.14 0.13 0.11
≥2.0, ≤2.5 0.03 0.06 0.02 0.04 0.06 0.04 0.07
≥2.5, ≤3.0 0.04 0.03 0.03 0.02 0.04 0.08 0.03
≥3.0 0.16 0.20 0.28 0.17 0.40 0.27 0.09
Avg. RMSD 1.53 1.98 3.19 2.15 3.69 2.13 1.46
  1. athe date are from reference [30].
  2. bthe date are from reference [29].
  3. cthe date are from reference [31].
  4. dthe date are from reference [32].
  5. ethe date are from reference [28].
  6. fthe date are derived from running Dock6 with default parameters.