Figure 6

Score distributions and congruence of variant calls in next generation sequencing data. While a clear separation of score populations is observable for the diploid A. thaliana and the haploid E. coli, only a shallow minimum can be observed in case of D. melanogaster. Hence, in the latter case our model automatically adjusts to the data such that the calling appears to be more conservative: less than 4 percent of the calls are not supported by any caller and 92% of its calls are supported both by GATK and SAMtools. On the other hand, our model calls more variants in the other two cases.