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Table 5 Some useful metrics of disorder associated genes

From: A multiobjective approach for identifying protein complexes and studying their association in multiple disorders

Disease category No. of associated genes No. of interaction in human PPI Density Semantic similarity
Bone 180 94 0.0163 0.5676
Cancer 869 725 0.0019 0.8931
Cardiovascular 332 457 0.0083 0.7374
Connective_tissue 149 75 0.0068 0.7146
Dermatological 270 154 0.0042 0.6381
Developmental 143 219 0.0216 0.7589
Ear, nose, throat 177 183 0.0117 0.8277
Endocrine 305 572 0.0123 0.8432
Gastrointestinal 110 52 0.0087 0.5819
Hematological 389 755 0.0100 0.6449
Immunological 290 658 0.0157 0.8159
Metabolic 638 2,088 0.0103 0.7458
Muscular 294 1,183 0.0275 0.6421
Neurological 917 898 0.0021 0.7811
Nutritional 51 82 0.0643 0.6536
Ophthalmological 563 555 0.0037 0.7035
Psychiatric 75 49 0.0177 0.7032
Renal 170 131 0.0091 0.6545
Respiratory 79 1 0.00032 0.7023
Skeletal 278 186 0.0048 0.6679
Unclassified 64 6 0.0030 0.5080
Multiple 721 427 0.0016 0.8019