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Fig. 11 | Algorithms for Molecular Biology

Fig. 11

From: BicNET: Flexible module discovery in large-scale biological networks using biclustering

Fig. 11

Advanced aspects of BicNET: 1 allowing symmetries within the discovered modules through iterative sign adjustments to model biological entities simultaneously involved in up- and down-regulatory interactions, and 2 allowing plaid effects through the guided inclusion of new interactions explained by cumulative contributions to model biological entities involved in multiple biological processes (commonly associated with overlapping regions or hub-nodes within a network)

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