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Table 1 Inferred human gut Firmicutes CsoR meta-regulon

From: A Bayesian inference method for the analysis of transcriptional regulatory networks in metagenomic data

eggNOG / COG

eggNOG 4.0 annotation

Domains

Mapped operons

Operons for analysis

P(R|D)

Operon with COG1937

Operon with COG2217

Dual sites

COG1937

Transcriptional repressor

IPR003735

530

332

1

332

94

93/221

COG2217

p-type ATPase

IPR006121, IPR023214, IPR008250

1580

422

1

84

422

94/204

NOG218972

Heavy-metal-associated domain

IPR006121

16

7

1

1

2

3/7

NOG72602

Predicted membrane protein

IPR018758

16

5

1

0

0

1/4

NOG109008

N/A

IPR018242

18

5

1

0

0

0/5

COG2836

Membrane protein

IPR006121, IPR003834, IPR018758

36

8

1

0

1

1/3

NOG81268

Heavy-metal-associated domain

IPR006121

34

6

1

0

1

1/5

  1. Operons for analysis denotes the total number of operons mapping to each eggNOG/COG after sensitivity adjustment. P(R|D) designates the posterior probability of regulation for the eggNOG/COG. The Operon with COG1937 and Operon with COG2217 columns indicate the number of genes mapping to an eggNOG/COG that were assigned to an operon containing also COG1937 or COG2217, respectively. Dual sites denotes the number of sequences mapping to an eggNOG/COG harboring two high-confidence sites, out of the total number of sequences mapping to that eggNOG/COG with high-confidence sites