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Fig. 5 | Algorithms for Molecular Biology

Fig. 5

From: Analysis of gene copy number changes in tumor phylogenetics

Fig. 5

An example to test whether Leaf1 can be optimally “lifted” to its parent node Node6 in MPT. a A MPT on 5 leaves and 3 internal nodes. b Leaf1 and compute the ranges of possible values to internal nodes, except Node6, in MPT Leaf1 in a bottom-up phase. c Assign the cell count pattern of Leaf1 to the root of MP T Leaf1, and determine the values for other internal nodes in MPT Leaf1 in a top-down phase. d Contract all trivial branches in MPT Leafi and derive RSMT*. Nodes with identical cell count patterns are shown in the same color and the Steiner node in RSMT* is colored in red

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