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Table 5 Values of the six criteria for the FS dataset

From: Aligning coding sequences with frameshift extension penalties

fs_open_ cost

fs_extend_cost (# CDS pairs)

Method

Identity_ NT

Identity_ AA

Gap_ init

Gap_ length

FS_init (avg)

FS_ length

−10

−1 (212)

fse0

166002

325212

895

60662

226 (1.06 ± 0.25)

20219

fse

165720

325026

901

60624

216 (1.01 ± 0.14)

18705

macse_p

166167

324999

1445

61562

432 (2.03 ± 3.06)

22742

needlenuc

172959

321348

5053

60038

2103 (9.91 ± 26.73)

29616

−0.5 (386)

fse0

252590

464712

2400

114859

482 (1.24 ± 0.47)

31777

fse

251647

463407

2387

115269

401 (1.03 ± 0.19)

26982

macse_p

253715

465594

4161

117165

1306 (3.38 ± 4.53)

41742

needlenuc

279682

452673

19408

113195

8032 (20.80 ± 31.02)

68226

−0.2 (619)

fse0

371062

641748

5334

204370

805 (1.30 ± 0.52)

43381

fse

370260

640377

5270

204806

688 (1.11 ± 0.33)

37376

macse_p

374729

646893

9308

208344

2893 (4.67 ± 5.34)

72030

needlenuc

442564

618270

48799

209420

19751 (31.90 ± 34.48)

141217

−20

−1 (161)

fse0

123814

244350

461

40315

168 (1.04 ± 0.20)

17770

fse

123610

244149

468

40195

164 (1.01 ± 0.14)

16924

macse_p

123541

243591

709

40585

223 (1.38 ± 1.03)

18119

needlenuc

125452

242742

1493

39031

650 (4.03 ± 5.85)

19405

−0.5 (189)

fse0

147476

291147

549

49485

197 (1.04 ± 0.20)

19599

fse

147401

291048

557

49363

194 (1.02  ± 0.16 )

19279

macse_p

147143

290271

838

49841

260 (1.37 ± 0.98)

19976

needlenuc

149551

289086

1872

47515

808 (4.27 ± 6.17)

21440

−0.2 (216)

fse0

161906

318117

723

55383

225 (1.04 ± 0.20)

21300

fse

161865

318099

732

55393

223 ( 1.03 ± 0.18)

21115

macse_p

161622

317205

1061

55715

306 (1.41 ± 0.99)

21997

needlenuc

165260

315531

2851

53613

1186 (5.49 ± 6.82)

24403

−30

−1 (71)

fse0

47071

91266

230

26303

76 (1.07 ± 0.26)

12845

fse

46872

91032

233

26183

72 (1.01 ±  0.12)

12302

macse_p

46936

90876

372

26325

118 (1.66 ± 1.25)

13142

needlenuc

48290

91017

866

26135

391 (5.50 ± 5.67)

13829

−0.5 (154)

fse0

120558

237768

445

37975

159 (1.03 ± 0.18)

17554

fse

120504

237678

452

37851

157 (1.01 ±  0.14)

17319

macse_p

120338

237084

691

38047

212 (1.37 ± 1.00)

17926

needlenuc

122084

236904

1321

37531

575 (3.73 ± 5.14)

18877

−0.2 (178)

fse0

137451

271041

525

46049

184 (1.03 ± 0.18)

18995

fse

137440

271008

531

45917

183 (1.02 ± 0.17)

18872

macse_p

137175

270258

803

46187

244 ( 1.37 ± 0.97)

19395

needlenuc

139489

269139

1803

44303

779 (4.38 ± 6.27)

20859

  1. For varying values of the parameters fs_open_cost and fs_extend_cost, the number of CDS pairs in the dataset is given. The values of the criteria for the fse, fse0, macse_p, needlenuc methods are indicated. For each method, the average number of FS_init per alignment, with corresponding standard error values are also indicated
  2. The best results are indicated in italics