TY - JOUR AU - Doerr, Daniel AU - Balaban, Metin AU - Feijão, Pedro AU - Chauve, Cedric PY - 2017 DA - 2017/05/26 TI - The gene family-free median of three JO - Algorithms for Molecular Biology SP - 14 VL - 12 IS - 1 AB - The gene family-free framework for comparative genomics aims at providing methods for gene order analysis that do not require prior gene family assignment, but work directly on a sequence similarity graph. We study two problems related to the breakpoint median of three genomes, which asks for the construction of a fourth genome that minimizes the sum of breakpoint distances to the input genomes. SN - 1748-7188 UR - https://doi.org/10.1186/s13015-017-0106-z DO - 10.1186/s13015-017-0106-z ID - Doerr2017 ER -