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Table 3 Running time and average SPS with RNA MSA

From: HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing

  Φ RNA (small) Φ RNA (large)
Time Memory (GB) Avg SPS Time Memory (GB) Avg SPS
MUSCLE 1 h 25 m ~ 13 0.821
MAFFT 45 m 33 s ~ 10 0.815
Clustal-Omega 4 h 16 m ~ 10 0.835
HAlign 1 h 32 s ~ 2 0.631 3 h 15 m ~ 10 0.631
HAlign-II 23 m 34 s ~ 1 0.633 59 m 42 s ~ 2 0.633