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Table 2 Rank correlation p-values for URM (U) and seed target (S) motifs

From: Regmex: a statistical tool for exploring motifs in ranked sequence lists from genomics experiments

 

Regmex

Brownian bridge

Regmex modified rank sum

DRIMust

Sylamer

GCCCGG

1.23e−230*

5.91e−70

3.07e−116

1.20e−34

CCCGGT

1.77e−210*

4.55e−52

8.19e−110

5.95e−27

TGCCCG

9.90e−200*

3.35e−49

1.23e−98

4.13e−50

ATGCCC

6.63e−125*

1.73e−24

2.09e−65

2.89e−42

AATGCC

1.76e−60*

1.90e−10

7.78e−38

1.44e−29

CCGGTa

1.91−45*

1.09e−05

6.55e−31

5.00e−06

CCGGTt

2.80e−17*

0.020

2.58e−15

n.s.

CCGGTg

6.49−11*

n.s.

1.27e−09

n.s.

CCGGTc

1.16e−06

0.0044

1.06e−11*

n.s.

tAATGC

n.s.

n.s.

0.00014*

n.s.

cAATGC

n.s.

n.s.

0.0018*

n.s.

  1. p-value outputs for 6-mer motifs overlapping a 10-mer spiked into a randomly re-ordered gene list for three methods, Regmex, Sylamer and DRIMust. Motif bases overlapping the 10-mer spike-in are in capital
  2. n.s. Not significant
  3. *Most significant method