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Fig. 1 | Algorithms for Molecular Biology

Fig. 1

From: Differentially mutated subnetworks discovery

Fig. 1

Identification of subnetworks with significant difference in mutation frequency in two set of samples \({\mathcal {C}}, {\mathcal {D}}\). The blue subnetwork is significantly more mutated in \({\mathcal {D}}\) than in \({\mathcal {C}}\), but it is not detected by methods that look for the most significantly mutated subnetworks in \({\mathcal {C}}\) or in \({\mathcal {D}}\) or in \({\mathcal {C}}\cup {\mathcal {D}}\), since the orange subnetwork is in each case mutated at much higher frequency

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