Fig. 6From: A multi-labeled tree dissimilarity measure for comparing “clonal trees” of tumor progressiona True clonal tree depicting the evolution of hypothetical tumor. b–e Hypothetical trees inferred by methods for reconstructing history of tumor evolution (input data to these methods is assumed to be obtained from the hypothetical tumor mentioned in the description of ‘True tree’). These trees are used as examples which demonstrate limitations of the existing measures for calculating similarity/“dissimilarity” between true and each of the four inferred trees (details provided in "The existing measures and their limitations" section). In "Application to the synthetic examples with the 56 available ground truth" section we discuss the application of MLTD in calculating similarities between these pairs of treesBack to article page