Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

Table 4 Empirical dataset summary statistics

Dataset	Number of taxa	NHD	Gappiness	Ref align length	Est align length	SP-FN	SP-FP
IGIA	110	0.606	0.915	10,368	6675	0.734	0.784
IGIB	202	0.579	0.910	10,633	7379	0.825	0.864
IGIC2	32	0.533	0.700	4243	3514	0.689	0.715
IGID	21	0.719	0.782	5061	3023	0.874	0.904
IGIE	249	0.451	0.838	2751	2775	0.393	0.376
IGIIA	174	0.668	0.814	6406	7005	0.816	0.800
PA23	142	0.293	0.267	3991	3552	0.078	0.077
PE23	117	0.300	0.612	9436	10,083	0.202	0.213
PM23	102	0.361	0.797	10,999	8803	0.262	0.288
SA16	132	0.212	0.205	1866	1673	0.031	0.028
SA23	144	0.304	0.460	4048	3678	0.077	0.081

The empirical study made use of reference alignments (“Ref align”) from the CRW database [3]. The reference alignments were curated using heterogeneous data including secondary structure information. The column description is identical to Table 2, where the empirical study made use of reference alignments in lieu of the simulation study’s true alignments